polygenicity

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mqar96 / twas-xcal

Ancestry-aware null calibration for TWAS (XCAL-t): polygenic inflation is ancestry-specific. Counted-false-positive benchmark, 1000 Genomes x 12,478 MESA models, Biobank Japan height application.

python bioinformatics gwas linkage-disequilibrium genomics computational-biology population-genetics statistical-genetics twas predixcan multi-ancestry 1000-genomes transcriptome-wide-association polygenicity

Updated Nov 9, 2026
Python

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