Simplified model of mTOR written using PySB. mTOR is modeled such that its activation is due to insulin receptor activation, and inhibited by binding of rapamycin-FKBP complex.
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Updated
Dec 6, 2022 - Python
Simplified model of mTOR written using PySB. mTOR is modeled such that its activation is due to insulin receptor activation, and inhibited by binding of rapamycin-FKBP complex.
Open-source research on the ecological and biochemical mechanisms of regeneration. Models the interaction between Basidiomycete metabolites, mTOR/AMPK/SIRT1 signaling, and TP53/autophagy balance — bridging ecology, computation, and cellular longevity.
Python-powered provenance-first atlas of mTOR signaling with disease overlays, inhibitor annotations, and fail-closed AI research triage.
Curated interaction graph of the mTOR signalling pathway (mTORC1/mTORC2) with a Python package, figures and an interactive explorer
Claude Code plugin and Gemini CLI extension for Oliver's mTOR Atlas (read-only MCP server)
MTOR sequence-to-structure bioinformatics case study covering biological databases, variants, evolutionary analysis, structure, and pathway interpretation.
Metabolic Calculator
Oliver's mTOR Atlas: the mTOR pathway, mapped by what the evidence can actually carry. 400+ curated studies, each labelled by the kind of study behind it (human, animal, molecular), linked to genes, drugs and diseases.
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