[adamjohnwright]

Fixes #131. Both reference-entity query sites (bulk prefetch Query 5 and the `get_reference_entity_id` fallback) keyed on an HGNC ReferenceDNASequence under `referenceGene`; Release 98 carries none (0 of 106,316 RGPs), so every protein silently lost its reference and balancing/slot-binding/identity signatures died build-wide (deltasignal specs/151 amendment 1 has the trace).

New predicate (verified identical behaviour on Release 97 and 98 Neo4j side by side): a human `ReferenceGeneProduct` (isoforms carry the label) with any `referenceGene` → return `re.stId`. Proteins resolve to the same ids the HGNC chain returned; RNAs (never matched the old chain — its 97 population was exactly RGP 15,636 + isoform 2,078, zero RNA) stay excluded by the label; viral proteins still return None, so pathogen handling is unchanged. The one behaviour delta: 189 human gene products whose HGNC rows were missing from release slices (IG V segments, UBE2O, SORCS3, CD21) now resolve — 7 of deltasignal's 125 build pathways touch any of them.

Loud failure: a build resolving zero references over ≥10 accessioned entities now raises with a named error instead of silently building a wrong network; `LNG_ALLOW_NO_REFERENCES=1` is the explicit escape hatch for a deliberately non-human build.

Acceptance gate (running next, before merge): rebuild Release 97 with this branch and compare content-identical (the specs/065 content-labelling method) against the frozen catalog `20261026-1349_8b6527e`; the 7 touched pathways get individual inspection if they differ. Then rebuild 98 and re-run the deltasignal specs/150 replication.

Note: `tests/test_network_invariants.py::TestAllPathwaysHaveContent::test_main_edges_proportional_to_best_matches[Class_I_MHC...]` fails identically on main in this environment (it reads a locally generated network — the defective 98 build); not introduced here. The rest of the suite: 771 passed.

🤖 Generated with Claude Code

[adamjohnwright]

G1 acceptance gate PASSED: the 92 catalog pathways rebuilt on Release 97 from this branch (build 20261113-1235_baf608b_hgncfix97, seed recorded, 92/92 complete, balancer and slot binding alive in the log) are content-identical to the frozen catalog 20261026-1349_8b6527e — zero differing pathways under the specs/065 content labelling, zero side-table row-count mismatches across every CSV of every pathway. The 189 newly-resolving references change no signature decision in our scope. Record: deltasignal specs/152 (G1).